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Examination of circulating inflammatory markers showed that RETA moderately increased IL-6 concentrations, whereas withdrawal significantly elevated plasma IL-6 concentrations compared to Veh

Because more research is needed on the benefits of L-carnitine, people should be aware that they may not always see desired effects from L-carnitine supplementation

Physicians should educate patients on the symptoms of kidney issues, like swelling, confusion, or a decrease in urine

Labs are not required for most patients, though the provider can require them based on medical history

doi: 10.3389/fphar.2025.1696506 Received 02 September 2025 Revised 02 November 2025 Accepted 12 November 2025 Published 26 November 2025 Volume 16 - 2025 Edited by Javier Echeverria, University of Santiago, Chile Reviewed by Kwazi Gabuza, South African Medical Research Council, South Africa Zheng Xu, The Seventh Clinical Medical College of Guangzhou University of Chinese Medicine, China Updates Copyright 2025 Zhang, Shi and Shi